Where Does American Cruise Lines Go Explore Top Destinations

American Cruise Lines sails to over 30 iconic U.S. destinations, from the rugged coastlines of Alaska to the historic waterways of the East Coast and the sun-drenched charm of the Southeast. Top itineraries include the Columbia & Snake Rivers, Puget Sound, and the Mississippi River, offering intimate, all-American voyages with unmatched regional experiences.

Key Takeaways

• Explore U.S. coastlines: Sail scenic routes from Alaska to Florida.
• River cruises offered: Discover Mississippi, Columbia, and Ohio rivers.
• Small ships access: Dock at unique ports larger ships can’t reach.
• Year-round options: Choose warm escapes or fall foliage voyages.
• All-inclusive value: Enjoy meals, excursions, and entertainment included.
• Local culture focus: Engage with regional history and cuisine onboard.

Where Does American Cruise Lines Go? Explore Top Destinations

When it comes to experiencing the beauty of the United States from a unique perspective, few options compare to the comfort and charm of American Cruise Lines (ACL). Known for its small-ship luxury and immersive itineraries, American Cruise Lines offers travelers the chance to explore some of the most scenic and culturally rich regions of the country—all from the comfort of a modern, intimate cruise ship. Whether you’re a seasoned cruiser or new to river and coastal voyages, ACL’s destinations span the East Coast, the Mississippi River, Alaska, and beyond, offering a blend of natural wonders, historic landmarks, and authentic local culture.

Unlike large ocean liners that dock in major ports and offer limited access to inland waterways, American Cruise Lines specializes in small-ship cruising, allowing passengers to venture into narrow rivers, secluded bays, and remote coastal towns. With a fleet of U.S.-built, U.S.-flagged vessels designed to navigate America’s inland and coastal waters, ACL provides an experience that’s both luxurious and deeply personal. From the lush forests of the Pacific Northwest to the antebellum charm of the Southeast, and from the rugged beauty of Alaska to the vibrant river towns of the Mississippi, ACL’s itineraries are carefully curated to showcase the best of what the U.S. has to offer. In this guide, we’ll explore the top destinations where American Cruise Lines goes and what makes each journey unforgettable.

1. The Majestic Mississippi River: A Journey Through American History

The Mississippi River is more than a waterway—it’s a living chronicle of American history, culture, and natural beauty. American Cruise Lines offers several itineraries along the Mississippi, from short 5-day cruises to comprehensive 15-day voyages that trace the river from its headwaters to the Gulf of Mexico. These journeys are ideal for history buffs, music lovers, and nature enthusiasts alike.

Classic Mississippi River Itineraries

One of the most popular offerings is the “Great River Journey”, a 15-day cruise from New Orleans to St. Paul. This route covers over 1,200 miles and includes stops in iconic river towns like Vicksburg, Natchez, Memphis, and Hannibal, Missouri. Each stop features guided shore excursions that highlight local history, architecture, and cuisine. For example, in Natchez, guests can tour antebellum homes such as Longwood and Stanton Hall, while in Memphis, a visit to Beale Street and the National Civil Rights Museum offers deep cultural insights.

Shorter options include the 8-day “Lower Mississippi River” cruise, which sails between New Orleans and Memphis, and the 5-day “Upper Mississippi River” cruise from Dubuque to St. Louis. These shorter itineraries are perfect for first-time cruisers or those with limited time.

Onboard Experience and Unique Features

ACL’s riverboats, such as the American Harmony and American Jazz, are designed specifically for the Mississippi’s narrow channels and shallow waters. With capacities of just 180–200 guests, the ships offer an intimate, uncrowded experience. Onboard amenities include spacious staterooms with private balconies, fine dining featuring regional specialties (think gumbo, catfish, and sweet potato pie), and nightly entertainment with live jazz, blues, and riverboat storytelling.

One standout feature is the “River Heritage” lecture series, where historians and local experts give talks on topics ranging from the Civil War to the evolution of American music. Passengers also enjoy scenic views from the open-air observation deck, where the river’s ever-changing landscape—cypress swamps, cotton fields, and river bluffs—unfolds like a moving painting.

Tips for Travelers

• Pack layers—Mississippi weather can vary widely, especially in spring and fall.
• Take advantage of early-morning excursions to avoid crowds at popular sites like the Vicksburg National Military Park.
• Don’t miss the onboard cooking demos—many feature local chefs preparing regional dishes.

2. The Pacific Northwest: Cruising the Columbia and Snake Rivers

For travelers seeking dramatic landscapes and a blend of natural and cultural history, the Pacific Northwest is a must-visit destination. American Cruise Lines offers several cruises along the Columbia and Snake Rivers, which flow through the states of Oregon, Washington, and Idaho. These waterways are framed by towering basalt cliffs, lush forests, and fertile agricultural regions, making them a feast for the senses.

Itineraries and Key Stops

The 8-day “Columbia & Snake Rivers” cruise typically begins in Portland, Oregon, and ends in Clarkston, Washington (or vice versa). Along the way, passengers visit:

• The Dalles, OR: Explore the Columbia River Gorge and the historic Columbia Gorge Discovery Center.
• Richland, WA: Learn about the Manhattan Project at the Hanford Site and visit the REACH Museum.
• Lewiston, ID: The deepest inland seaport in the U.S., with access to the Hells Canyon National Recreation Area.
• Palouse Falls, WA: A breathtaking 200-foot waterfall, best viewed from the observation deck or a short hike.

These cruises also include scenic transit through the four dams and locks on the Snake River, where passengers can watch the ship “climb” or “descend” hundreds of feet—a fascinating engineering marvel.

Wildlife and Scenic Highlights

The Columbia-Snake corridor is a haven for wildlife. Passengers often spot bald eagles, ospreys, deer, and even the occasional black bear along the riverbanks. The region is also known for its vineyards and fruit orchards, and many excursions include wine tastings at local wineries such as Snoqualmie Vineyards and Maryhill Winery.

One of the most memorable experiences is the sunset cruise through Hells Canyon, the deepest river gorge in North America—deeper than the Grand Canyon. The dramatic cliffs, carved by millions of years of erosion, glow in the evening light, creating a truly magical atmosphere.

Traveler Tips

• Bring binoculars for birdwatching and wildlife spotting.
• Visit during late spring or early fall for the best weather and fewer crowds.
• Try local specialties like Walla Walla sweet onions and Columbia Valley wines.

3. New England and the Canadian Maritimes: Coastal Charm and Fall Foliage

For those who love coastal scenery, historic lighthouses, and the vibrant colors of fall, American Cruise Lines’ New England and Canadian Maritimes itineraries are a dream come true. These cruises typically run from late summer through October, capitalizing on the region’s famous autumn foliage and crisp maritime air.

Itinerary Overview

The 11-day “New England & Canadian Maritimes” cruise sails from Boston to Halifax, with stops in:

• Portland, ME: Explore the Old Port district and visit the Portland Head Light, the most photographed lighthouse in the U.S.
• Bar Harbor, ME: Gateway to Acadia National Park, where passengers can hike, bike, or take a scenic drive to Cadillac Mountain.
• Saint John, NB: Home to the Reversing Falls Rapids and the historic Loyalist City.
• Halifax, NS: Visit the Maritime Museum of the Atlantic and pay respects at the Titanic victims’ cemetery.
• Charlottetown, PEI: Birthplace of Canadian Confederation and home to the famous Green Gables house.

Onboard and Onshore Experiences

ACL’s coastal ships, such as the American Constitution, are designed for open-ocean and sheltered bay navigation. With wraparound promenade decks and large viewing windows, passengers can enjoy panoramic views of rocky coastlines, fishing villages, and migrating whales.

Onshore excursions are tailored to the season. In September and October, foliage tours take guests to the best vantage points in Acadia, the White Mountains, and Prince Edward Island. In summer, whale watching, kayaking, and lobster-bake dinners are highlights. The onboard naturalist often gives talks on marine life, including humpback, minke, and pilot whales that frequent the Gulf of Maine.

Practical Tips

• Book early—these cruises sell out quickly due to high demand for fall foliage.
• Pack a windbreaker and waterproof jacket; coastal weather can be unpredictable.
• Try local seafood—especially Maine lobster, PEI mussels, and Nova Scotian scallops.

4. Alaska: The Last Frontier by Small Ship

While many associate Alaska with massive cruise ships, American Cruise Lines offers a more intimate and immersive way to explore The Last Frontier. ACL’s Alaska cruises focus on the Inside Passage, a network of protected waterways, fjords, and island archipelagos that stretch from Washington to Alaska.

Alaska Itineraries and Highlights

The 8-day “Alaska’s Inside Passage” cruise typically departs from Juneau and ends in Sitka (or reverse), with stops in:

• Skagway: Gateway to the Klondike Gold Rush National Historical Park and the White Pass Railway.
• Haines: A quiet town known for its bald eagle gatherings and outdoor adventures.
• Glacier Bay National Park: A UNESCO World Heritage Site where passengers can witness glaciers calving into the sea.
• Tracy Arm Fjord: A narrow, ice-choked fjord with towering cliffs and cascading waterfalls.
• Ketchikan: The “Salmon Capital of the World,” with access to totem pole parks and rainforests.

Wildlife and Natural Wonders

ACL’s small ships can navigate closer to wildlife and natural features than larger vessels. Passengers frequently see:

• Bald eagles perched in Sitka spruce trees
• Humpback whales breaching near the ship
• Bears foraging along the shoreline
• Sea otters floating in kelp beds

One of the most unforgettable moments is glacier viewing. The ship slows to a near stop as a massive iceberg breaks off and crashes into the water—a phenomenon known as “calving.” The onboard naturalists provide expert commentary on glaciology and climate change.

Travel Tips for Alaska

• Layer your clothing—Alaska’s weather changes rapidly, even in summer.
• Bring a high-quality camera with a zoom lens for wildlife photography.
• Participate in the onboard “Alaska Native Culture” sessions, which include storytelling and traditional dance.

5. The Southeast and Florida: Coastal Gems and River Towns

From the historic charm of Charleston to the sun-soaked beaches of Florida, American Cruise Lines’ Southeast and Florida itineraries offer a blend of coastal elegance and riverine beauty. These cruises are perfect for travelers who want to explore the American South without the crowds of larger ships.

Popular Routes and Destinations

The 7-day “Southeast Coast” cruise typically sails between Charleston, SC, and Amelia Island, FL, with stops in:

• Savannah, GA: Stroll through the historic district and visit Forsyth Park.
• Jekyll Island, GA: Explore the historic Millionaire’s Village and pristine beaches.
• St. Augustine, FL: The oldest continuously inhabited European-established settlement in the U.S.
• Fernandina Beach, FL: Known for its Victorian architecture and shrimp boats.

ACL also offers Florida Intracoastal Waterway cruises, which follow the protected waterways along the Atlantic coast, avoiding open-ocean passages. These itineraries include stops in Palm Beach, Vero Beach, and the Everglades.

Unique Onboard and Onshore Experiences

The Southeast cruises emphasize Southern hospitality and cuisine. Onboard, passengers enjoy dishes like shrimp and grits, Lowcountry boil, and peach cobbler. Evening entertainment often includes live bluegrass and jazz music.

Onshore, excursions range from historic home tours (such as the Andrew Low House in Savannah) to eco-tours of the Everglades, where guests can see alligators, manatees, and wading birds. In St. Augustine, a visit to the Castillo de San Marcos, a 17th-century Spanish fort, offers a glimpse into colonial history.

Tips for Southeast Cruising

• Visit during spring or fall for milder temperatures and fewer mosquitoes.
• Try local craft beers and spirits—Savannah and St. Augustine have thriving microbrewery scenes.
• Bring a hat and sunscreen—the Florida sun is intense, even in winter.

6. The Great Lakes and St. Lawrence Seaway: A Freshwater Adventure

For a lesser-known but equally spectacular experience, American Cruise Lines offers cruises on the Great Lakes and St. Lawrence Seaway. These freshwater voyages explore five of the world’s largest lakes—Superior, Michigan, Huron, Erie, and Ontario—along with the historic St. Lawrence River.

Itinerary and Key Stops

The 10-day “Great Lakes & St. Lawrence Seaway” cruise sails from Chicago to Montreal, with stops in:

• Traverse City, MI: Known for its cherry orchards and Sleeping Bear Dunes.
• Mackinac Island, MI: A car-free island with Victorian architecture and fudge shops.
• Toronto, ON: Visit the CN Tower, Royal Ontario Museum, and Niagara Falls (via excursion).
• Quebec City, QC: A UNESCO World Heritage Site with cobblestone streets and French charm.
• Montreal, QC: Explore Old Montreal, the Underground City, and Mount Royal.

Onboard and Scenic Highlights

ACL’s Great Lakes ships are equipped with large observation decks and floor-to-ceiling windows, offering stunning views of lighthouses, shipwrecks, and the vast, open water. The onboard historian often discusses the region’s maritime heritage, including the Great Lakes shipping industry and the War of 1812.

One of the most unique experiences is passing through the Welland Canal, which lifts ships over 300 feet to cross the Niagara Escarpment. Passengers can watch the locks in action from the deck—a fascinating display of engineering.

Traveler Tips

• Visit in late summer or early fall for the best weather and fewer bugs.
• Try local specialties like Chicago deep-dish pizza, Montreal bagels, and Great Lakes whitefish.
• Bring a good book—the long stretches of open water are perfect for relaxation.

Comparison of American Cruise Lines Destinations

Destination	Duration	Best Time to Visit	Key Highlights	Ship Type
Mississippi River	5–15 days	Spring, Fall	Historic towns, jazz, antebellum homes	Riverboat (e.g., American Harmony)
Pacific Northwest	8 days	Spring, Fall	Columbia Gorge, Hells Canyon, wine country	Riverboat (e.g., American Song)
New England & Maritimes	11 days	Late Summer, Fall	Fall foliage, lighthouses, Acadia National Park	Coastal ship (e.g., American Constitution)
Alaska	8 days	Summer (June–Aug)	Glaciers, whales, Inside Passage	Coastal ship (e.g., American Constellation)
Southeast & Florida	7 days	Spring, Fall	Coastal towns, Everglades, historic homes	Coastal ship (e.g., American Star)
Great Lakes	10 days	Summer, Early Fall	Niagara Falls, Quebec City, ship locks	Coastal ship (e.g., American Spirit)

Where does American Cruise Lines go? The answer is as diverse as the country itself. From the deep history of the Mississippi River to the wild beauty of Alaska, from the autumn splendor of New England to the freshwater majesty of the Great Lakes, ACL offers a unique, intimate, and enriching way to explore America’s most iconic waterways. With small ships, expert-led excursions, and a focus on local culture and cuisine, each journey is more than a vacation—it’s a deep dive into the heart of American life. Whether you’re drawn to history, nature, or simply the joy of slow travel, American Cruise Lines has a destination that’s perfect for you. So pack your bags, grab your camera, and set sail on an adventure you’ll never forget.

Frequently Asked Questions

Where does American Cruise Lines go for coastal adventures?

American Cruise Lines offers coastal voyages along the East Coast, including the Atlantic Intracoastal Waterway, New England, and the Southeast. Popular stops include Charleston, Savannah, and historic ports in Maine.

Does American Cruise Lines sail to Alaska?

Yes, their Alaska cruises explore the Inside Passage, with stops in Juneau, Ketchikan, and Skagway. These itineraries highlight glaciers, wildlife, and Native Alaskan culture.

Where does American Cruise Lines go in the Pacific Northwest?

They operate river and coastal cruises in the Pacific Northwest, including the Columbia and Snake Rivers. Destinations feature Portland, Astoria, and scenic landscapes like Hells Canyon.

Are there American Cruise Lines itineraries in the Mississippi River region?

Absolutely. Their Mississippi River cruises cover New Orleans to St. Louis, with stops in Memphis, Natchez, and Vicksburg. Small ships dock at charming river towns.

What international destinations does American Cruise Lines visit?

While most itineraries are U.S.-based, they occasionally offer cruises to Canada’s St. Lawrence Seaway and the Great Lakes. Check their website for seasonal international options.

Where does American Cruise Lines go for unique themed cruises?

Themed voyages include Civil War history along the South Carolina coast, fall foliage in New England, and culinary-focused trips in the Pacific Northwest. Each cruise offers onboard enrichment programs.